Articles

Glutathione Serum Is Making Waves: PURCELL's Product Development Stands Out with Unique Technology & Clinical Trials

2025.01.21

In recent years, the global popularity of Korean skincare is remarkable. PURCELL, which has gained attention centered around glutathione serum, rapidly garnered support from many people after its arrival in Japan in February last year.

This time, we focus on PURCELL's "L-GLUTATHIONE FLEXIBLE LIPOSOME." Listening to the reasons for spotlighting glutathione, which is a trending ingredient, and the development process reveals a unique brand charm that goes beyond merely responding to trends and customer needs.

PURCELL's Product Development Focused on Function, Purity, and Concentration

PURCELL develops products through repeated original ingredient development based on meticulous research and effect verification through clinical trials. What specific research and experiments are being conducted?

PURCELL establishes three standards: high purity, high functionality, and verification, proposing a High-Dose Treatment that solves skin issues through advanced science.

The selected ingredients, which meet PURCELL's strict standards, first undergo In-vitro testing (all experiments conducted in artificial environments such as test tubes, petri dishes, or culture flasks) to confirm their functionality initially.

Next, researchers and marketers participate in tests alongside subjects in In-vivo trials (conducted on humans to obtain objective evidence of the safety and effectiveness of test products) to verify the actual effect on human skin.

Finally, formal clinical institutions conduct tests to validate the product's efficacy. Through these processes, PURCELL's products are born.

Glutathione began being sold as a pharmaceutical ingredient in 1960, and later it was used in the beauty field, recognized as an ingredient in treatments like "white-drops." Although it is not a new noteworthy ingredient, what is the reason that PURCELL focused on glutathione?

PURCELL is a brand that resolves skin concerns by using functional ingredients in high purity, and glutathione has been proven effective over many years, which also piqued our interest.

Glutathione is a compound made of three amino acids: glycine, cysteine, and glutamic acid, known for its antioxidant properties.

All these components are essential for the skin, making it suitable for solving skincare concerns for those who wish to enhance moisture and achieve a radiant complexion.

However, given that glutathione poses challenges that need to be addressed alongside its attractiveness, PURCELL invested significant effort into developing new technology for its inclusion in products.

What challenges does glutathione present, and what new technology has been developed to solve them?

Glutathione can only exert its effects when absorbed by the skin while maintaining its antioxidant properties, but the ingredient possesses a rapid oxidation characteristic, making it critical to determine how to facilitate absorption before it oxidizes.

Thus, PURCELL focused on research to suppress the damage and oxidation of glutathione and deliver it to the skin in a stable state.

Using PURCELL’s original technology, glutathione was transformed into deformable liposomes, leading to the creation of a new ingredient that enhanced stability and absorption rates.

The "L-GLUTATHIONE FLEXIBLE LIPOSOME" has smaller molecules than typical liposomes, allowing it to reach every corner of the stratum corneum where it needs to be delivered.

As a skincare ingredient, glutathione has been refined to overcome its shortcomings, representing a unique PURCELL formulation that differentiates it from other glutathione cosmetics.

Glutathione with a Unique Scent: What Do Users Say?

Did you encounter difficulties in development, such as separation or achieving the ideal texture when creating highly pure, highly concentrated, and highly absorbent formulations of glutathione?

PURCELL's liposomal glutathione is a unique ingredient that improves absorption and stability compared to traditional glutathione materials, making it easier to incorporate into cosmetics.

As a result, we can incorporate high concentrations of glutathione in products, allowing users to experience its characteristic strong protein scent.

We determined that adding fragrance to mask glutathione's distinct scent does not align with PURCELL's pursuit of high purity, so we chose to preserve the original scent during product development.

You may initially resist the smell of glutathione, but the strength of the scent indicates that it is highly pure and concentrated.

Are there ingredients that work well or poorly with glutathione?

Glutathione is a gentle ingredient, and there are no incompatible components. It can be safely applied alongside other products or ingredients.

To support the brightening effect of glutathione, it is advisable to use it with other brightening ingredients like niacinamide and arbutin.

The "L-GLUTATHIONE FLEXIBLE LIPOSOME" serum also contains niacinamide and arbutin, helping to enhance skin hydration while improving clarity and addressing skin concerns.

What feedback have you received from users about the "L-GLUTATHIONE FLEXIBLE LIPOSOME" serum? Are there any differences between Korea and Japan?

PURCELL continues to grow with passion and love while receiving various reviews and before-and-after images from customers who have actually used our products.

Users have shared positive feedback, saying it is “easy to feel the effects and I keep repurchasing it,” “the unique scent is addictive,” and “my sensitive skin has stabilized.”

In Korea, in addition to "L-GLUTATHIONE FLEXIBLE LIPOSOME," we also see a wide range of products being loved, such as "PICXELL BIOM" containing 2 billion lactic acid bacteria per 1ml and the "24/7 COLOSTRUM PORE DEFENSE AMPOULE with PICXELL BIOM," which can be used over makeup to address shine and dryness.

In Japan, "L-GLUTATHIONE FLEXIBLE LIPOSOME" is the most popular product.

We are sincerely grateful for the high evaluations we receive for our uniquely developed glutathione-based cosmetics crafted with heartfelt dedication.

We will continue to work hard so more customers can experience the allure of PURCELL products.

PURCELL conducts clinical trials while establishing development standards, overcoming ingredient weaknesses with technology, and supporting users in resolving their skin concerns. We look forward to focusing on new technologies and products in the future.

Text by Rie Tsugita (Beautician, Writer)